In love, chemist Paul Matthews visits with gypsy Madame Rosa to get assistance. Quickly understanding he could be just a hopeless nerd, she gifts him Love Potion No. 8, making anyone who wears it irresistible to the opposite sex for a few hours. Paul and animal psychologist coworker Diane Farrow opt to test it. The awkward group suddenly find themselves alluring to anyone they approach, but soon realize they are attracted to one another.